It is a method of delivering the drug directly into the blood stream without having to pass the oral or alimentary mucous layer. In this method of administration, drug is applied on to skin or other body surfaces. Drugs are applied topically to the skin or mucous membranes, mainly for local action. Confirm that the patient can take or receive the medication by the ordered route. What does conjunctival route of administration mean. Routes of drug administration advantages of inhalation rapid action of the drug, with local effects with in the respiratory tract potent drugs may be given in small amounts, minimizing the side effects convenience and comfort of the patient disadvantages of inhalation requires cooperation of the patient in proper breathing techniques for effectiveness adverse systemic side effects may result. Pharmacokinetics of different routes of administration of. If necessary, calculate the dose and have another nurse calculate the dose as well. The path taken by the drug to get into the body is known as the route of drug administration.
Routes of administration pharmacology linkedin slideshare. Start studying 8 routes of administration of drugs. Precautions drug should usually be injected slowly. In this lesson, we defined that a parenteral drug administration is the delivery of a medication by injection into the body, and discussed the common types of injections to include. Path by which a drug, fluid, poison, or other substance is taken into the body. The pharmacokinetic parameters of four different routes of administration of a single dose of 400 microg of misoprostol were studied.
The various routes of administrations are classified into following categories. Dec 21, 2016 routes of drug administration for mbbs 1st year dr. If you alter the work, you may not share or distribute the modified work. Describe the various dosage forms available for medications. Drug administration routes science topic the various ways of administering a drug or other chemical to a site in a patient or animal from where the chemical is absorbed into the blood and. Right route again, check the appropriateness of the route ordered. Routes of drug administration oral po oral administration will be covered in more detail in subsequent chapters. Introduction a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body. This route is where a medicament is applied on to skin to produce its effects. The oral route of administration is the safest, most economical and the most convenient way of giving medicines. The production of this text has raised many questions concerning the data available relating to this method of medication administration.
Do not administer drugs via tubes that are being used for aspiration or are on free. The three main parenteral routes of drug administration are iv, im, and sc, and in all cases administration is usually via a hollow needle. This table is for illustrative purposes only and is subject to change. Routes of administration inhalation route preferred route because onset is rapid smaller doses are needed compared to the oral route side effects e. Correlate the dosage forms with the appropriate route of administration.
A method in which a drug is taken into the body listed from slowest to fastest. Generally, an ebook can be downloaded in five minutes or less. Routes of administration of a drug are determined by its physical and chemical properties, patient characteristics and the rapidity of response desired. R outes of drug a dministration to laboratory a nimals common routes. Because the muscles lie below the skin and fatty tissues, a longer needle is used. Intravenous administration merits bypass first pass metabolism100% quick onset of action in uncooperative and unconscious patients those with nausea and vomiting hypertonic solutions and irritants large volumes amount of drug can be controlled accurately demerits antiseptic conditions depend on others painful and riskycant be recalled embolism suspensionsoily. We report here on the absorption and the systemic biological. Route of administration should address three basic criteria. A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body routes of administration are generally classified by the location at which the substance is applied. Sep 14, 2017 this video will help you to understand about basic pharmacology like what is drug what is pharmacokinetics what is pharmacodynamics routes of drug administration. Drugs are usually injected into the muscle of the upper arm, thigh, or buttock. Routes of drug administration pharmacology 3571 with. High molecular weight drugs in general, and peptides in particular, are usually delivered by parenteral route because they are poorly absorbed or degraded in the gastrointestinal tract.
Advantages safe convenient self administered, pain free, noninvasive and easy to take economical compared to other parentral routes usually good absorption takes place along the whole length of the gi tract no need for sterilization. A route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body. Pharmacokinetics of rectal compared to intramuscular paracetamol. A route of administration in pharmacology and toxicology is the path by which a drug, fluid. Drug absorption the rate at which a drug reaches it site of action depends on. Routes of drug administration the route of administration roa that is chosen may have a profound effect upon the speed and. Administration of drugs by injection and other routes. Drug begins breaking down in the stomach and is absorbed into. Implications for drug administration site of drug delivery most drugs absorbed in the jejunum drug absorption may be reduced due to ph alkaline environment or delivery beyond site of absorption function of enteral tube aspiration free drainage multilumen tubes. Use of aseptic technique very very important intravenous iv injections fast action due to avoidance of gi absorption intradermal injected into the dermis.
Routes of drug administration 1st edition elsevier. Pravin prasad 2nd year resident, md clinical pharmacology maharajgunj medical campus 18th december, 2016 3rd poush, 2073, sunday 2. Obtain appropriate information before administering a drug by injection to ensure patient safety. Parenteral drug administration their types, advantages. It also places the drinker at risk of accidents, arrests, poor job. The intramuscular route is preferred to the subcutaneous route when larger volumes of a drug product are needed. The rectal route has been used for administration of. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Before injecting, make sure that the tip of the needle is in the vein. This route is one of the safest route as the drug cannot product poisonous effects. A scheme of the different sites for parenteral drug administration is presented in figure 6.
Selecting a right route of drug administration by a physician improves patients health. Drug rehab centers facility may result in withdrawal tendencies and can lead to various mental as well as physical problems. Routes of drug administration for mbbs 1st year dr. A free powerpoint ppt presentation displayed as a flash slide show on id. Intravenous route advantages iv is the most common parenteral route. Alternatively, a drug reaches the bloodstream through the lymphatic vessels see figure. Mar 10, 2020 drug administration routes science topic the various ways of administering a drug or other chemical to a site in a patient or animal from where the chemical is absorbed into the blood and. Most of the drugs can be administered by variety of routes. May 22, 2016 different routes of administration, their advantages and disadvantages, suitable dosage forms to be delivered. Swallowed through the mouth into the stomach and digestive tract b. Administration of a drug to the conjunctiva, the most frequently used mode of ocular drug delivery. Classification routes of administration can broadly be divided into.
That is the drug acts only at the site of application and. Preparing to administer a drug drugs local effect applied directly to skin, tissue, or mucous membranes systemic effect given by routes that allow the drug to be absorbed or distributed into the bloodstream pay close attention dose route form of medication. Each route of administration has distinct advantages and disadvantages. Aerosols localtopical route of drug administration in this route the drug is applied on the skin. Routes of drug administration play a major role in a medical treatment. This route of administration is possible if the drug is in liquid dosage form. To optimize therapy, it is desirable to search for nonparenteral routes of administration and to deliver the drug in a controlledrelease fashion. Purchase routes of drug administration 1st edition. Routes can also be classified based on where the target of action is. Dosage form design may also be used modify the rate of absorption. Alternative routes of drug administration transdermal. Routes of drug administration 1 topical medication. A route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body classification routes of administration can broadly be divided into. Absorption after oral administration can be quite variable.
Routes of drug administration for bns 1st year slideshare. A drug given parenterally is one given by a route other than the mouth topical dosage forms are considered separately. Drug administration drugs msd manual consumer version. Routes of drug administration to laboratory animals authorstream. Route of administration an overview sciencedirect topics. Routes of drug administration advantages of inhalation rapid action of the drug, with local effects with in the respiratory tract potent drugs may be given in small.
Working with accuracy objectives after completing this chapter, the student will be able to. Extrapolation of mdma findings from animals to humans requires assessment of pharmacokinetics in various species, and lowdose administration data from rats are lacking. In this study, we examine mdma pharmacokinetics in rats given low 2 mgkg and high 10. However, the result obtained in our experiment show that the duration taken for drug action through subcutaneous route which is 28 minutes is shorter than the duration. Download free medication administration record pdf. Systemic route a enteral route b parenteral route 1. Oral route the most common route of drug administration. Parenteral route of administration and dosage forms a drug given parenterally is one given by a route other than the mouth topical dosage forms are considered separately. How to download notes in pdf from solution pharmacy facebook group using laptop using mobile. Define the routes of administration for medications. Injectable preparations are usually sterile solutions or suspensions of drug in water.
Techniques used for drug administration by pulmonary route two techniques can be used for administration of drugs by pulmonary route. Common examples include oral and intravenous administration. After a drug is injected, it then moves into small blood vessels capillaries and is carried away by the bloodstream. A route of administration in pharmacy is the path by which a drug is taken into the body. The drug is injected into the subcutaneous tissues of the thigh, abdomen and arm, e. For many pscbased therapies, the target site is usually at or near the site of cell loss or injury e. Jun 10, 2015 most of the drugs can be administered by variety of routes. The rectal route of drug administration is a practical. Different routes of administration, their advantages and disadvantages, suitable dosage forms to be delivered. Oral the most convenient and most commonly used route of administration examples are tablets, capsules, and liquids. The duration taken for drug action of subcutaneously administrated drug should be longer than the duration taken for drug action of other parenteral route of drug administration. In this administration the drug is administered in the gaseous form.
Iv delivery permits a rapid effect and a maximal degree of control over the circulating levels of the drug. This presentation describes various routes of drug administration. This video will help you to understand about basic pharmacology like what is drug what is pharmacokinetics what is pharmacodynamics routes of drug. The nursing profession has shown an increasing interest in this route of drug. You are free to copy and communicate the work in its current form for noncommercial purposes, as long as you attribute the state of queensland, queensland ambulance service and comply with the licence terms. Gastrointestinal oral per os through the mouth gavage into the stomach via a tube or gavage needle rectal per rectum into the rectum via the anus npo nil per os nothing by mouth. For the subcutaneous route, a needle is inserted into fatty tissue just beneath the skin. Routes of drug administration to laboratory animals.
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